Introduction:: through a retrospective study concerning the experience of our center in patients affected by Neurally Mediated reflex Syncope (NMS), we wanted to verify not only the diagnostic yield of ILR but its possible placebo therapeutic effect.
Methods: in the context of patients affected by a severe clinical presentation of NMS, identified through a careful clinical evaluation, we selected those who followed a diagnostic iter using the ILR.
Results: we analysed 84 patients (39 male and 45 female, mean age 71 years), during the period 2009-2013. 34 patients (40.5%) had not recurrences after a mean follow-up (FU) of 35 months, among these 17 patients concluded a FU of 4 years. 50 patients (59.5%) had recurrences and a specific diagnosis after an average period of 7 months
Conclusions: we found an important number of patients who show a disappearance of syncope during an observation period of 2-3 and 4 years. At first glance this result could be explained considering the possible placebo therapeutic effect of ILR.