Introduction: Cryo-balloon catheter ablation (CB) has proven effective in the definitive treatment of paroxysmal atrial fibrillation However, the isolated efficacy of CB restoring and maintaining sinus rhythm in patients with persistent long standing atrial fibrillation (AF) is less knowed in a medium -long terms follow-up. We analyzed the acute results and the medium-long term follow-up of our patients suffering AF and initially treated with CB.
Methods: A total of 35 patients (28 male (80%) and 7 female (17%), mean age 59 ±11 and 64±5 years respectively with AF were treated with CB. The mean time duration of stable arrhythmia was 4±3 years (2-11). PV/LA morphological and structural data are shown in table 1.

Results:Are showed in table 2.
Conclusions: CB technique is useful to treat persistent long standing Atrial Fibrillation with 46% success rate maintaining sinus rhythm without medication at 2,5 years, increasing by 23% to 69% when antiarrhythmic drugs are added. Patients without Structural Heart Disease along with those who sinus rhythm was restored during CB showed the best results.