LEFT VENTRICULAR LEAD PLACEMENT IN THE LATEST ACTIVATED REGION GUIDED BY CORONARY VENOUS ELECTROANATOMIC MAPPING

M. Maines, C. Angheben, D. Catanzariti, I. Di Matteo, M. Moretti, M. Del Greco

Department of Cardiology, Santa Maria del Carmine Hospital, Rovereto, Italy

Abstract

Introduction : Left ventricular (LV) lead placement in the latest activated region is an important determinant of response to cardiac resynchronization therapy (CRT).
Purpose: Aim of this study was to evaluated the latest activated region in coronary sinus (CS) in patients underwent CRT devices implant.
Methods and results: 46 consecutive CRT patients (38 males, age 72.9±7.3 years), underwent intra-procedural coronary venous EAM using EnSite NavX. A guidewire was used to map the coronary veins during intrinsic activation. The latest activated region were reported in Table 1.
Conclusions: Coronary venous EAM can be used intraprocedurally to guide LV lead placement to the latest activated region. This approach especially contributes to optimization of LV lead electrical delay in patients with multiple target veins. Conventional anatomical LV lead placement strategy does not target the vein with maximal electrical delay in many of these patients.


Population, annual CRT implants rates and normalized implant rates per million inhabitants
Delay in LAO Latest activation during sinus rhythm – Number of patients Latest activation during RV pacing - Number of patients
anterior 2 10
Antero-lateral 8 8
Lateral 27 18
Postero-lateral 8 10
Posterior 1 0
Delay in RAO
Basal 25 16
Medium 16 15
Apical 5 15