DIFFERENCES IN RISK FACTORS OF PM/ICD POCKET INFECTION AND LEAD DEPENDENT INFECTIVE ENDOCARDITIS IN PATIENTS QUALIFIED FOR TRANSVENOUS LEAD EXTRACTION
B. Ma?ecka, A. Wysoki?ski
1.Department of Electrocardiology, John Paul II Hospital in Krakow, Collegium Medicum Jagiellonian University, Krakow, Poland; 2. Department of Cardiology, Medical University in Lublin, Lublin, Poland
Introduction: Evaluation of risk factors of isolated pocket infection (PI) and isolated lead dependent infective endocarditis (LDIE) in patients referred for transvenous lead extraction (TLE).
Methods: Retrospective analysis of1554TLE procedures with 2571extracted leads. The examined population consisted of: group A-231 patients with isolated PI (59 F, mean age 69.7±12.9 years), group B-152 patients with isolated LDIE (55 F, mean age 64.1±15.6 years).Patientsqualified for TLE due to non-infective indications (923)andpatientswith clinical manifestation of concomitantPI and systemic infection markers or LDIE (248)were excluded from the analysis. The remaining parameters were assessed: the patient’s age and gender, number of device-related procedures performed before TLE, lead number and dwell-time, number of non-functional leads.Diabetes and renal failure were assessed in the part of population with complete information in the database.
Results: The results are presented in the table.
Conclusions:
- 1. Two variables: patient’s ageand lead dwell time correlated with the PM/ICD infection type.
- 2. Patients with PI were significantly older and had shorter lead dwell time in comparison with patients with LDIE.
Population, annual CRT implants rates and normalized implant rates per million inhabitants
| Indication for TLE |
PI Group A |
LDIE Group B |
TOTAL |
P value
total
|
P value
A vs B
|
| Number of patients | 231 | 152 | 631 | - | |
| Female patient | 59/231 (25.4%) | 55/152 (36.2%) | 182/631 (28.8%) | P=0.0651 | |
| Age of patients[mean] | 69.7±12.9 | 64.1±15.6 | 67.4±14.0 | P=0.0007 | P=0.0007 |
| Number of leads in the heart | 2.00±0.75 | 2.19±0.94 | 2.09±0.81 | P=0.0688 | |
| Age of leads [mean] | 71.4±52.3 | 86.5±56.9 | 76.3±53.4 | P=0.0201 | P=0.0248 |
| Number of device-relatedprocedures before TLE | 2.23±2.90 | 2.23±2.90 | 2.24±2.07 | P=0.9352 | |
| Number of non-functional leads | 0.23±0.57 | 0.33±0.70 | 0.29±0.65 | P=0.2384 | |
| Diabetes # | 38/198 (19.2%) | 34/139 (24.5%) | 124/582 (21.3%) | P=0.5082 | |
| Renal failure ## | 10/198 (5.0%) | 11/139 (7.9%) | 34/580 (5.9%) | P=0.4935 | |
|
| # incomplete information in 49 pts (33 pts PI, 13 pts LDIE) |
## incomplete information in 51 pts (33 pts PI, 13 pts LDIE) |
