THE EFFECT OF POST-PROCEDURAL CARDIAC ENZYME SURGEON THE LONG-TERM RECURRENCE RATES AFTER CRYO-BALLOON ABLATION FOR ATRIAL FIBRILLATION
B. Candemir, S. Aghdam, M. Kilickap, C.T. Kaya, AT. Altin, A. Ongun, V.K. Vurgun, O. Akyurek, M. Guldal, C. Erol
Ankara University School of Medicine, Ankara, Turkey
Objectives: Cardiac enzymes, representing myocardial injury, increase after surgical or catheter ablation for atrial fibrillation
(AF). However, significance and impact of this injury on recurrence rates after cryoballoon ablation (CBA) have not been studied before.
We aimed to examine the effect of atrial injury on long-term recurrence rates in patients who underwent CBA for atrial fibrillation.
Methods&result: Blood samples for CKMB and Troponin I were collected before and 24 hour after CBA in 33 consecutive patients
with paroxysmal AF. At 6-month follow-up, 10 (30%) patients had recurrence. Both CKMB and troponin levels increased significantly 24 hour
after CBA. Pre-procedural troponin level was higher in patients with recurrence but barely missed statistical significance
(0.04 ± 0.17µg/L vs. 0.17 ± 0.36µg/L; p=0.055).Post-procedural and difference values for troponin I or CKMB did not differ
in 2 groups. Table-1 summarizes patient characteristics according to AF recurrence.
Conclusions: Post-procedural cardiac enzyme surge does not predict long-term recurrences in patients who
underwent cryoballoon ablation for AF.
|
No Recurrence (n=23)
|
Recurrence(n=10)
|
p
|
Age |
51.9±12.2 |
64.0±11.7 |
0.013 |
Male Gender |
12 (52) |
5 (50) |
1.000 |
CHADS2VASC Score |
1.4±1.0 |
3.3±1.7 |
0.007 |
Heart failure |
0 (0) |
2 (20) |
0.085 |
Coronary artery disease |
4 (17) |
6 (60) |
0.035 |
|
|
|
|
Left atrial diameter (cm) |
4.3±0.4 |
4.3±0.4 |
1.000 |
|
|
|
|
|
|
|
|
|
|
|
|
Preprocedural CKMB |
1,9 ± 1,2 |
1,9 ± 1,6 |
0.724 |
Postprocedural CKMB |
20,2 ± 17,5 |
26,3 ±30,9 |
0.938 |
Difference_CKMB |
18.3±17.6 |
24.4±29.7 |
0.860 |
Preprocedural Troponin |
0.04 ± 0.17 |
0.17 ± 0.36 |
0.055 |
Postprocedural Troponin |
3.40 ± 2.45 |
7.44 ± 10.43 |
0.164 |
Difference_Troponin |
3.4±2.5 |
7.3±10.1 |
0.137 |