Introduction: In some cases permanent acute pulmonary vein (PV) reconnection (AR) appears immediately after adenosine infusion. Study evaluated if adenosine-test facilitates AR in observation period.
Methods: Study included 134 patients with paroxysmal and persistent atrial fibrillation, who had undergone Lasso-guided PVI. All patients were randomized to 2 groups. In ATP-group (65 patients) adenosine-test (without dormant conduction ablation) was performed followed by 30’ observation period. In control-group (69 patients) 30' observation period was applied only.
Results: In 134 patients 268 pairs of ipsilateral PVs were isolated. AR occurred in 49 (38%) of ipsilateral PV pairs (41 patients – 63%) in ATP-group and in 45 (33%) of ipsilateral PV pairs (43 patients – 62%). Difference between groups didn't show statistical significance (?2 =0,76; p=0,38). In ATP-group dormant conduction was revealed in 31 (23%) of ipsilateral PV pairs (27 patients – 42%). Only in 16 of 31 (52%) PVs dormant conduction site corresponded to the site of AR. The agreement between methods is fair (Kappa = 0,24; p = 0,004).
Conclusions: Adenosine infusion does not facilitate acute pulmonary vein reconnection in observation period after initial isolation.