RELATIONSHIP OF A CHA2DS2-VASc SCORE AND PEAK VELOCITY OF LEFT ATRIAL APPENDAGE WITH LEFT ATRIAL THROMBUS FORMATION IN PATIENTS WITH NONVALVULAR ATRIAL FIBRILLATION

T. Harada, M. Nakajima, Y.Takagi, M. Takano, E. Nakano, Y. Takimura, K. Yoneyama, S. Nishio, T. Furukawa, K. Suzuki, Y. Akashi

Division of Cardiology, St. Marianna University, Kawasaki, Japan

Abstract

Objectives : The aim of this study was to evaluate the relationship of CHA2DS2-VASc score and peak velocity (PV) of left atrial appendage (LAA) with left atrial (LA) thrombus identified by transesophageal echocardiography (TEE).
Methods: The study population consisted of 431 patients with NVAF who were calculated CHA2DS2-VASc score. The PV of LAA was calculated using TEE images.
Results: Among 228 patients of CHA2DS2-VASc score >2, LA thrombus was present at 21 (44%) of 47 patients who showed a PV of LAA< 30m/sec, compared with 59(32%) of 181 patients who showed a PV of LAA >30m/sec (p=0.12). However, among low risk 203 patients assessed by CHA2DS2-VASc score <1, LA thrombus was present at 13 (34%) of 38 patients who showed a PV of LAA< 30m/sec, compared with 20 (12%) of 165 patients who showed a PV of LAA >30m/sec (p=0.0024).
Conclusions: LA thrombus formation is not related with PV of LAA in patients with high CHA2DS2-VASc score, however, in patients with NVAF calculated low CHA2DS2-VASc score a PV of LA could play an important role of LA thrombogenic circumstance.