OUTCOME OF PATIENTS WITH CARDIAC RESYNCHRONIZATION THERAPY. COMPARISON BETWEEN ELDERLY AND ADULT PATIENTS
N. Martinenghi, N. Galizio, M. Mysuta, J.L. Gonzalez, F. Robles, A. Palazzo, X. Vallejo Deeb, G. Carnero, H. Fraguas
Department of Cardiac Electrophysiology, University Hospital Favaloro Foundation, Buenos Aires, Argentina
Introduction: There is little evidence about the benefit of CRT in elderly. The aim of the study was to assess the outcome of CRT in elderly patients (pts) compared with adults.
Methods: A prospective analysis was performed in 32 elderly pts (?70 years) and 65 adults (21-69 years) with idiopathic dilated or ischemic cardiomyopathy who fulfilled CRT-D indications. Pts were considered responders if there was a LVEF improvement ?5% and/or a reduction ?1 NYHA functional class. Responder rate, LVEF improvement and cardiovascular mortality (CVM) were assessed. Mean follow-up was 21 months (2-49).
Results: Mean age was 75.2±10.5 years in elderly pts and 58.8±10 years in adults (p<0.05). Responder rate was 75% vs 73.8% (ns). Mean LVEF improvement was 6.2 ±10% vs 9.3 ±10% (ns). CVM was 3.12% vs 3.07% (ns) among elderly and adults respectively.
Conclusions: In our study population, CRT was as effective in elderly as in adults in terms of responder rate, improving LVEF and CVM. Age alone should not be a restricting factor for CRT in heart failure patients.
