fibrillation is a common rhythm disorder, which is related to a higher risk of
thrombembolism resulting in a high rate of cerebral stroke or transient
ischemic attacks. According to the CHADS2- or CHA2DS2Vasc-Score there is an
indication for oral anticoagulation to prevent patients from mostly disabling
strokes. However, more than 50% of patients are not adequately treated with
oral anticoagulation due to different reasons, especially contraindications.
More than 90% of thrombi develop
in the left atrial appendage (LAA), which lead to the idea of developing
devices to exclude the LAA from the systemic circulation to prevent patients
from embolisations. Another approach is surgical ligation or removal of the LAA
during operation procedures.
Credits: Dr. Peter B. Sick