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Paroxysmal Lone Atrial Fibrillation Is Associated With An Abnormal Atrial Substrate: Characterizing The �Second Factor�

Stiles et al, recently published a study titled “Paroxysmal Lone Atrial fibrillation is associated with an abnormal atrial substrate: Characterizing the Second Factor” in The Journal of The American College of Cardiology.” Authors demonstrated structural and electrophysiological abnormalities in the atria of patients with paroxysmal lone atrial fibrillation (AF). The authors postulate that these factors are likely contributors to the “second factor” that predisposes to the development and progression of AF.

Credits: Charles R. Mitchell, MD; Mithilesh K. Das, MD