Left atrial appendage (LAA) exclusion with the use of the AtriClip (AtriCure, Inc., OH, USA) device has been shown to be a safe, effective, and durable strategy predominantly to reduce the lifelong risk of thromboembolism and stroke in patients with atrial fibrillation (AF). We present a case showing electrical isolation of the LAA after its exclusion with the AtriClip device during hybrid ablation for the treatment of longstanding persistent AF. Our case demonstrates the effectiveness of the AtriClip device in not only mechanically occluding the LAA but also electrically isolating it, thereby addressing an electrical driver of AF in addition to reducing its thromboembolic sequelae.